Sad to see Shelley Duvall in that condition and becoming entertainment for "Dr. Phil." I only saw her in The Shining like probably everyone else here. María Conchita Alonso was like every where in the 80s. Or at least in movies like Predator 2 and I believe Running Man. I saw Jasmine Guy on the street once. I was surprised and shocked because I thought I knew her but then I realized it was one of those things when you see somebody so much on TV. I just walked past her. She was with this big tall guy.
Does Nastassja Kinski count? She's definitely my icon of the 80s. But, she didn't exactly vanish afterwards.
Really more of a 70's "chick" but I really had a fascination with Caroline Munro in my younger days. I had about 15 8x10 stills hung on the living room wall. To this day I say she is one of the most beautiful women ever.
From the 80s the first that always springs to my mind is Diane Franklin as mentioned earlier in this thread.